組織工程化神經修復周圍神經缺損（2）

       第三屆國際神經再生高峯論壇(INRS2013)——We previously demonstrated that a natural and biodegradable polysaccharide, chitosan, was biocompatible with neuroglial cells by virtue of its positive effects on the adhesion,survival,migration, and proliferation of Schwann cells. We also demonstrated that the in vitro and vivo biodegradation product of chitosan, chitooligosaccharide, could support neural cell adhesion and encourage neuronal differentiation and neurite outgrowth through the up-regulation of neurofilament and N-cadherin expression.