胶质瘢痕与功能再生(2)
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胶质瘢痕与功能再生(2)
第三届国际神经再生高峰论坛(INRS2013)——While the astrocytic scar is one major barrier to regeneration, regeneration failure is also due in part to the synaptic entrapment of growth cones on NG2 glia (following MAC attack) through actions of LAR family receptors that cause an overly adhered synaptic state. Inactivation of LAR or PTP sigma in our scar model in vitro releases entrapment and allows for motile growth cones.
Guests :
Prof. Jerry Silver
Keyword :
胶质细胞 胶质瘢痕 瘢痕模型 生长锥Year:2013